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CENAPT resource - Determination of Natural Product Integrity

This webpage contains a series of information (e.g, links towards educative resources, articles) related to the definition of Natural Product Integrity and the relevant parameters necessary for its determination.

Table of Content

  1. NIH Resources
  2. HerbalGram Articles on Botanical Integrity
  3. Educative & Useful Resources
  4. Worlwide Pharmacopoeia resources for plant-based medicinal products and dietary supplements

1. NIH Resources

📜 NCCIH Policy: Natural Product Integrity

This webpage contains information regarding requirements for grant applications.

📜 ODS Resources for Product Integrity

This webpage contains a list of web-based resources and articles to guide the scientists in fulfilling the NCCIH Natural Product Policy for Dietary Supplement Research.

2. HerbalGram Articles on Botanical Integrity

These articles from the UIC Botanical Dietary Supplement Research Center define the notion of botanical integrity (BI) as resulting from the integration of Botanical, Chemical, and Biological Analyses. The first article also addresses the place and role of DNA barcoding. The second article focuses on techniques related to botanical examination (botany) and phytochemical analysis (chemistry), which are used to determine the Botanical Integrity of a given plant material.

Article 1: Definition of Botanical Integrity

BILogo
Botanical Integrity requires the integration of three fields of expertise: Chemistry (Phytochemistry), Botany (Identification methods), and Bioactivity (Bioactivity measurement and safety assessment).

Article 2: Traditional and Modern Analytical Approaches

BI

☝︎ Table of Contents
Combination of Analytical Techniques that Supports the Authentication and Phytochemical Characterization of Botanicals. The techniques are categorized as belonging to the botanical examination (Botany) vs phytochemical analysis (Chemistry), and are utilized to ultimately determine the Botanical Integrity (BI) of a given plant material. The more recent/modern approaches are highlighted in red, whereas the more traditional techniques are italicized.

3. Educative and Useful Resources

From the relevance of accurate botanical identification and plant naming, to Good Practices and Guidelines on plant collection.

4. Worlwide Pharmacopoeia resources for plant-based medicinal products and dietary supplements

World Health Organization:

Africa:

America:

United-States:

Asia:

1. Hong-Kong:

2. India:

3. Japan:

4. Korea:

Europe:

1. Germany:

  • German Commission E Monographs over 300 herbs, compiled the commission E since 1978, translated and published in English in 1998 by the American Botanical Council [ABC].

2. Great Britain: