CENAPT - University of Illinois at Chicago
Natural Products Events
07/2018 ASP 2018
04/2018 ICSB 2018
07/2017 ASP


📕 The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

McAlpine, James B. and Chen, Shao-Nong and Kutateladze, Andrei and MacMillan, John B. and Appendino, Giovanni and Barison, Andersson and Beniddir, Mehdi A. and Biavatti, Maique W. and Bluml, Stefan and Boufridi, Asmaa and Butler, Mark S. and Capon, Robert J. and Choi, Young H. and Coppage, David and Crews, Phillip and Crimmins, Michael T. and Csete, Marie and Dewapriya, Pradeep and Egan, Joseph M. and Garson, Mary J. and Genta-Jouve, Grégory and Gerwick, William H. and Gross, Harald and Harper, Mary Kay and Hermanto, Precilia and Hook, James M. and Hunter, Luke and Jeannerat, Damien and Ji, Nai-Yun and Johnson, Tyler A. and Kingston, David G. I. and Koshino, Hiroyuki and Lee, Hsiau-Wei and Lewin, Guy and Li, Jie and Linington, Roger G. and Liu, Miaomiao and McPhail, Kerry L. and Molinski, Tadeusz F. and Moore, Bradley S. and Nam, Joo-Won and Neupane, Ram P. and Niemitz, Matthias and Nuzillard, Jean-Marc and Oberlies, Nicholas H. and Ocampos, Fernanda M. M. and Pan, Guohui and Quinn, Ronald J. and Reddy, D. Sai and Renault, Jean-Hugues and Rivera-Chávez, José and Robien, Wolfgang and Saunders, Carla M. and Schmidt, Thomas J. and Seger, Christoph and Shen, Ben and Steinbeck, Christoph and Stuppner, Hermann and Sturm, Sonja and Taglialatela-Scafati, Orazio and Tantillo, Dean J. and Verpoorte, Robert and Wang, Bin-Gui and Williams, Craig M. and Williams, Philip G. and Wist, Julien and Yue, Jian-Min and Zhang, Chen and Xu, Zhengren and Simmler, Charlotte and Lankin, David C. and Bisson, Jonathan and Pauli, Guido F.
Natural Product Report ASAP, C7NP00064B (2018)
DOI:10.1039/C7NP00064B [OpenAccess]

📕 Pharmacognosy in the digital era: shifting to contextualized metabolomics

Allard PM, Bisson J, Azzollini A, Pauli GF, Cordell GA, Wolfender JL.
Current Opinion in Biotechnology ASAP, 57-64 (2018)

📕 Integrated analytical assets aid botanical authenticity and adulteration management

Simmler C, Graham JG, Chen SN, Pauli GF.
Fitoterapia ASAP, xxx-yyy (2017)
“How and why metabolomics should be integrated in the quality control toolset for the determination of botanical authenticity“

📕 The Essential Medicinal Chemistry of Curcumin

Nelson KM, Dahlin JL, Bisson J, Graham J, Pauli GF, Walters MA
Journal of Medicinal Chemistry ASAP, xxx-yyy (2017)
DOI:10.1021/acs.jmedchem.6b00975 [OpenAccess]
Curcumin is an improbable lead for new drugs

📕 Improvements to the Practical Usability of the “Crystalline Sponge” Method for Organic Structure Determination

Greyson W. Waldhart, Neal P. Mankad, and Bernard D. Santarsiero
Organic Letters ASAP, xxx-yyy (2016)
Advancing the crystalline sponge technique for the structural analysis of small molecules

📕 Dissemination of original NMR data enhances reproducibility and integrity in chemical research

Bisson J, Simmler C, Chen SN, Friesen JB, Lankin DC, Pauli GF
Natural Products Reports ASAP, xxx-yyy (2016)
How dissemination of original NMR data could help chemical research integrity

📕 Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving

Pauli GF, Niemitz M, Bisson J, Lodewyk MW, Soldi C, Shaw JT, Tantillo DJ, Saya JM, Vos K, Kleinnijenhuis RA, Hiemstra H, Chen S, McAlpine JB, Lankin DC, Friesen JB
Journal of Organic Chemistry ASAP, xxx-yyy (2016)
DOI:10.1021/acs.joc.5b02456 [OpenAccess]
Raw NMR Data Sharing using QuILTs

📕 Holistic Analysis Enhances the Description of Metabolic Complexity in Dietary Natural Products

Simmler C, Kulakowski D, Lankin DC, McAlpine JB, Chen S and Pauli GF
Advances in Nutrition , 179-189 (2016)
The scope of this review, covering literature of the past 5 y, is to address the relevance of 1H-NMR–based metabolomics in food plant studies, including a comparison with MS-based techniques.

📕 Can Invalid Bioactives Undermine Natural-Product Based Drug Discovery

Bisson J, McAlpine JB, Friesen JB, Chen S, Graham J, Pauli GF
Journal of Medicinal Chemistry 59(5), 1671-1690 (2015)
DOI:10.1021/acs.jmedchem.5b01009 [OpenAccess]
Only 39 compounds cover the Natural Products most reported by occurrence, activity, and distinct activity